СИСТЕМНЫЕ МЕХАНИЗМЫ ИНДИВИДУАЛЬНОЙ СТРЕСС-УСТОЙЧИВОСТИ У ЭКСПЕРИМЕНТАЛЬНЫХ ЖИВОТНЫХ ПРИ СТРЕССАХ РАЗЛИЧНОЙ МОДАЛЬНОСТИ

RESULTS
During the experiment, the animals were divided into three groups: the 
first group is 28 rats (42, 4%), the second – 20 rats (30, 3%) and the 
third –
18 rats (27, 3%). Animals of the first group successfully 

performed in in apparatus 5-6 behavioral acts with the same duration 
per a session. Rats of the second group were daily increasing number of 
drinking behavioral acts, ranging from 3-4 to 7-9, the duration of 
which significantly reduced.
Rats of the third group during all the 

experimental sessions were conducting not more than two behavioral acts 
and their duration was 3-4 times higher than in the first and second 
groups.
Ratio of individual stages duration in behavioral acts to their total 
duration, revealed on the first day for all groups of rats, were 
reliably maintained without any significant changes in the subsequent 
days of experiments. Rats of the first and second groups most of the 
time (35-40%) were spending in "manipulation” zone (dT-4), and also 
during stages of dT-1 (15-18%) and dT-7 (25-30%). Rats of the third 
group most of the time (45-62%) were spending on the stage dT-7 and 
implementation of dT-1 and dT-4 have not exceeded 15-16% of the total 
behavioral acts duration. Rats of the first group consumed daily 20-22% 
in the apparatus of the total liquid amount. Rats of the second group 
were drinking in EA from 15% on the first testing day up to 32% of the 
total water volume in the last one. Rats of the third group showed 
index of 6 -7% during all days of the experiments. When this group of 
rats was given to drink after the experiments, they drank 93-94% of 
water from the total drunk liquid.
While evaluating the results, it can be assumed that the initial phase 
of the rats acquired behavior implementation (dT-1) is mainly 
associated with current activity initiation conditioned by motivation. 
Time indicators for complementation of the resultative (dT4 water 

consumption) and final (dT-7 - return to the starting position) stages 
of animals behavioral act characterize animals outcome evaluation 
processes and result parameters of the completed act and each 
subsequent behavioral act program formation in continuum of a goaldirected activity.
This allows us to use these values as reliable 

criteria for individual characteristics of animal behavior assessing. 
REFERENCES
1. Anokhin P.K. Biology and neurophysiology of the conditioned reflex 
// M.: Medicine, 1968. 548 pp.
2. Sudakov K.V. // Vestn. Ross. Akad. Med. Nauk. 2012. №8. P. 53-56.
3. Pevtsova E.I., Pevtsov S.Е., Tolpygo S.M. // Inventor's certificate: 
Russia, № 2013660110, 24.10.2013. 
4. Yucel Z., Sara Y., Duygulu P., Onur R., Esen E., Ozguler A.B. // J. 
Neurosci. Methods. 2009. V. 180. № 2. P. 234-242.
DOI:10.12737/12441

СИСТЕМНЫЕ МЕХАНИЗМЫ ИНДИВИДУАЛЬНОЙ СТРЕСС-УСТОЙЧИВОСТИ У 

ЭКСПЕРИМЕНТАЛЬНЫХ ЖИВОТНЫХ ПРИ СТРЕССАХ РАЗЛИЧНОЙ МОДАЛЬНОСТИ

А.А.Пермяков, Е.В.Елисеева, А.Д.Юдицкий, Л.С.Исакова