ВЕГЕТАТИВНАЯ РЕГУЛЯЦИЯ И АДАПТАЦИОННЫЕ ВОЗМОЖНОСТИ У ЮНОШЕЙ КОРЕННОГО НАСЕЛЕНИЯ РЕСПУБЛИКИ ХАКАСИЯ

islets, and one islet close associated with two ganglia; few endocrine 
cells in the nerve fibre and a single cell or few endocrine cells into 
the nerve bundles; and nerve endings in close proximity to islets of 
Langerhans or single endocrine cells. Such types of NIC were described 
in our previous studies [2,3].  In addition, the analysis of threedimensional reconstructions allowed us to identify the mixed type of 
NIC (one islet of Langerhans integrated with up to 2 NIC I and 3 NIC II 
simultaneously). The greatest number of such complexes was observed in 
the central part of the pancreas, while in the periphery they were not 
detected. These complexes were a very large size. 
In the middle fetal period (two fetuses, 20 gw), all of the described 
above NIC types were also detected. Moreover, the NIC of “transitional” 
type (a ganglion that passed there processes toward different islets) 
was revealed. Using the 3-D analysis, it was detected that one ganglion 
can give several of their processes to several different islets. Thus, 
a dense network was formed in which neural structures and islets of 
Langerhans were interconnected. However, by the end of middle fetal 
period (27 gw), the number of such complexes per pancreatic volume 
decreased and neural network became more sparse. In the late fetal (32 
and 37gw) and early postnatal periods, few NIC I were revealed mainly 
in the interlobular connective tissue. However, the ganglia in such NIC 
were smaller in size then in NIC I during the early and middle fetal 
periods.
This study confirms our assumption [3] that NIC can play a role in the 
formation of pancreatic neuro-endocrine functions and participate in 
the islets morphogenesis.
Supported by: Russian Foundation for Basic Research (15-04-03155)
References.
1. Ahrén B. //Diabetologia. 2012. Vol. 55. P. 3152–3154.
2. Krivova, Y.S., Proshchina, A.E., Barabanov, V.M., Saveliev, S.V.// 
Pancreas: Anatomy, Diseases and Health Implications, Nova Biomedical. 
2012. P. 55-88.
3. Proshchina A.E., Krivova Y.S., Barabanov V.M., Saveliev S.V. // 
Front.
Endocrinol. 
(Lausanne). 
2014. 
Vol. 

5.doi:10.3389/fendo.2014.00057. 
DOI:10.12737/12451

ВЕГЕТАТИВНАЯ РЕГУЛЯЦИЯ И АДАПТАЦИОННЫЕ ВОЗМОЖНОСТИ У ЮНОШЕЙ 

КОРЕННОГО НАСЕЛЕНИЯ РЕСПУБЛИКИ ХАКАСИЯ

Пуликов А.С., Москаленко О.Л., Маркович Е.Б.

Федеральное государственное бюджетное научное учреждение «Научно
исследовательский институт медицинских проблем Севера», г. Красноярск, 

Россия

gre-ll@mail.ru

Аннотация Проведено обследование 138 юношей-хакасов антропометрическими 
и функциональными методами с целью выявления вегетативной регуляции 
адаптивных 
возможностей 
молодого 
поколения 
коренного 
населения