МЕМБРАННЫЕ АСПЕКТЫ ПАТТЕРНА ВЕГЕТАТИВНОГО РЕАГИРОВАНИЯ И АДАПТАЦИОННЫЕ ВОЗМОЖНОСТИ У ЗДОРОВЫХ ШКОЛЬНИКОВ

The findings
The evidence of the chosen stress model consistency is the stress 

hormone level elevation in the blood of the experimental animals 
(catecholamines and 11-oxocorticosteroids) compared to the control 
group. The changes of the fetoplacental complex indices were found in 
all the female rats of the experimental group, both stress-resistant 
and non-stress-resistant, being more pronounced under the combined 
influence. Thus in the female rats resistant to stress it reached 
78,4%±8,5 (р<0,01), in the female rats predisposed to stress it was 
82%±5 (р<0,01) compared to the control group. The average mass of the 
fetuses produced by these rats was diminished by 24,4% (р≥0,05)  and by 
59% (р<0,05) respectively. Morphometry of the afterbirth showed the 
decrease in their mass and total area, on examination placentae seemed 
congestive plethoric with thrombosis spots at the periphery.

Thereby isolated immobilizing stress is not accompanied by 

morphoplacetal changes of the fetoplacental complex. Under the combined 
influence of stress and the REF adaptation mechanisms exhaustion of the 
mother-placenta-fetus system occurs being manifested as intrauterine 
fetus growth retardation with mass decrease, general embryonic 
mortality quotient elevation and degenerative afterbirth changes that 
may indicate placental deficiency [3]. The most noticeable changes were 
marked in the stress-non-resistant animals.

References:

1.
D. Belkin. Structural and functional changes in the organism under 

the technogenic rotating and intermittent electric fields and the 
mechanisms of their occurrence: Extended abstract of PhD dissertation 
(Biology). Novosybirsk, 1999.
2.
E.V. Koplik. The method of rat emotional stress resistance 

criterion establishment // Vestnik novykh med. techn. 2002. Vol. 9.#1
3.
A.P. Mylovanov. Pathology of the mother-placenta-fetus system: 

reference for doctors. Moscow: Medicine, 1999. 448 p.

DOI:10.12737/12349

МЕМБРАННЫЕ АСПЕКТЫ ПАТТЕРНА ВЕГЕТАТИВНОГО РЕАГИРОВАНИЯ И 

АДАПТАЦИОННЫЕ ВОЗМОЖНОСТИ  У ЗДОРОВЫХ ШКОЛЬНИКОВ

О.И. Зайцева1,2, Т.А. Колодяжная1

1ФГБНУ «НИИ медицинских проблем Севера», Красноярск, Россия

2 ГБОУ ВПО «КрасГМУ им. проф. В.Ф. Войно-Ясенецкого» МЗ РФ, Красноярск, 

Россия

impn@impn.ru

Абстракт. Адаптацию здоровых школьников оценивали по показателям 
чувствительности эритроцитарных мембран к
биорегуляторам вегетативной 

нервной системы с определением паттерна вегетативного реагирования на 
уровне 
биомембран 
методами 
спектрофлуориметрии 
и 
тонкослойной 

хроматографии. У здоровых школьников выделено несколько адаптивных 
типов мембранной регуляции  и установлены мембранассоциированные